Biosynthesis of Phosphonic and Phosphinic Acid Natural Products
نویسندگان
چکیده
منابع مشابه
Biosynthesis of Natural Products Containing Phosphonic Esters and Acids: Review
Natural products containing carbon-phosphorus bond (phosphonic esters and phosphinic acids) have found widespread use in medicine and agriculture. As such, natural products are the active components not only of most traditional medicines but also many modern medicines. Furthermore, because the structural diversity of natural products exceeds that readily achievable by chemical synthesis, and sy...
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Although natural products have been a particularly rich source of human medicines, activity-based screening results in a very high rate of rediscovery of known molecules. Based on the large number of natural product biosynthetic genes in microbial genomes, many have proposed "genome mining" as an alternative approach for discovery efforts; however, this idea has yet to be performed experimental...
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This article is part of the Thematic Series "Natural products in synthesis and biosynthesis". This is the second Thematic Series in the Beilstein Journal of Organic Chemistry focused on natural products. While the first Thematic Series summarized recent research work on the biosynthesis and function of natural products [1,2], the present Thematic Series deals with synthetic and biosynthetic asp...
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ژورنال
عنوان ژورنال: Annual Review of Biochemistry
سال: 2009
ISSN: 0066-4154,1545-4509
DOI: 10.1146/annurev.biochem.78.091707.100215